Conformational Change of the Corona virus Peplomer Glycoprotein at pH 8.0 (Potential Of Hydrogen) and 37°C Correlates with Virus Aggregation and Virus-Induced Cell Fusion
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC249489/
(JOURNAL OF VIROLOGY, American Society for Microbiology)
We have obtained biochemical and electron microscopic evidence of conformational changes at pH 8.0 and 37°C in the corona virus spike glycoprotein E2 (S). The importance of these changes is reflected in the loss of virus infectivity, the aggregation of virions, and increased virus-induced cell fusion at the same pH. Corona virus (MHV-A59) infectivity is exquisitely sensitive to pH (Potential of Hydrogen). The virus was quite stable at pH 6.0 and 37°C (half-life, -24 h) but was rapidly and irreversibly inactivated by brief treatment at pH 8.0 and 37°C (half-life, -30 min). Virions treated at pH 8.0 and 37°C formed clumps and large aggregates.
Alkaline water therapy as a potential systemic pH(Potential of Hydrogen) suppressant that could inhibit the activities of the COVID virus.
Until now, no promising scientific remedies or prevention techniques have been innovated. However, scientists and researchers are running to broaden efficient treatment strategies to cope with the novel corona viruses-19. Our modern-day world essentially feeds on acid-producing foods that immediately or silently preserve chemical pesticide residues and many chemical additives. Almost all toxic wastes that get into man’s body system contribute to a shift in the pH levels. Three major factors that aid infections with men have been identified as oxidation, acidification, and dehydration. Ionized and alkaline water has been identified as a panacea to most human diseases.
Man’s ultimate task is to manage and preserve his health, the following recommendations have been observed:
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